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. 2020 Nov 19;10:20189. doi: 10.1038/s41598-020-77217-5

Figure 5.

Figure 5

Proposed sex differences influence the maintenance of physiological conditions. Female and male physiological systems show inverse expression of PTEN and Klotho protein and different levels of mTOR and FoxO3a activity. However, comparisons of both sexes show no differences in AKT activity or apoptosis and autophagy processes, suggesting that these sex differences may be contributing to balancing mechanisms that establish similar outcomes between them.