Table 3.

Comparison between the new predictive model and each biomarker in terms of their power in differentiating Rupture group from Non-rupture group in patients with ACS.

	AUC (95% CI)	Cut-off point	Sensitivity	Specificity	p-value
Model	0.843 (0.757, 0.929)	0.61	62.2	97.6	–
sLOX-1	0.763 (0.660, 0.865)	236.4	50	95.35	0.0346
WBC	0.665 (0.548, 0.781)	6.9	75.61	52.38	0.0016
NGAL	0.609 (0.486, 0.731)	56.0	57.14	65.12	0.0004
MMP-9	0.645 (0.524, 0.766)	12.7	54.76	74.42	0.0002
Peak CK-MB	0.706 (0.587, 0.824)	7.3	57.9	83.3	0.0199

The cut-off point is calculated using the Youden’s index.

ACS acute coronary syndrome, AUC area under the curve, sLOX-1 soluble lectin-like oxidized low-density lipoprotein receptor-1, WBC white blood cell, NGAL neutrophil gelatinase-associated lipocalin, MMP-9 matrix metalloproteinase-9, CK-MB creatine kinase-muscle/brain.

p-values are the comparison results between new predictive model and each biomarker.