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. 2020 Nov 19;10:20166. doi: 10.1038/s41598-020-76754-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Comparison of the MR image (left) with the speed of sound image (right). The area enclosed in the yellow rectangle shows the Hoffa’s pad in both modalities. The correspondence is clear, even to the interface between the fat pad and the fat behind it, in the tibiofemoral space. The bone is clearly visible in the QT ultrasound image (QTUS). The high speed (light gray) muscle is seen in the SOS image and corresponds to the muscle showing up as a dark region on the MRI. The fat is light on the MRI, and dark (slow speed) on the QTUS image. The values from the QTUS image are quantitative correct to sub-mm resolution as shown in Tables 1 and 2.