Figure 7.

(A) Scheme of synergistic phototherapy for augmentation of antitumor immunity. Upon laser irradiation, designed nanoparticles can ablate the primary tumor through synergistic phototherapy, and the released TAA tend to trigger the antitumor immunity which contributes to the inhibition of tumor metastasis and relapse. (B) Temperature profiles of pure water and aqueous dispersions of PDA@UCNP nanoparticles (2 mg mL⁻¹) as a function of irradiation time (0–5 min). (C) The spectrum profiles of Ce6 absorption and PDA@UCNP emission excited with a 980 nm laser. (D) Tumor growth curve of 4T1 tumor-bearing mice with various treatments. Weight (E) and representative images (F) of the tumor from each group after euthanizing the animal on day 28. Copyright 2019, Wiley-VCH (Yan et al., 2019). **P < 0.01, ***P < 0.001, ****P < 0.0001 and ns: not significant (P > 0.05).