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Table 3. Risk stratification models for patients with pulmonary embolism by the risk of 30-day mortality81,174.

PESI Simplified PESI
Variable Point Variable Point
Patient characteristics Patient characteristics
Age Age in years Age 1 if age > 80 years
Male sex 10
Comorbidity Comorbidity
Cancer 30 Cancer 1
Heart failure 10
Chronic pulmonary disease 10
Chronic cardiopulmonary disease 1
Clinical finding Clinical finding
SBP < 100 mmHg 30 SBP < 100 mmHg 1
Heart rate ≥ 110 beats per minute 20 Heart rate ≥ 110 beats per minute 1
Respiratory rate ≥ 30 breaths per minute 20
Arterial oxygen saturation < 90%* 20 Arterial oxygen saturation < 90%* 1
Temperature < 36 °C 20
Altered mental status# 60
Risk category Point Mortality Risk category Point Mortality
Class I, very low ≤ 65 1.1% Low 0 1.0%
Class II, low 66-85 3.1% High ≥ 1 10.9%
Class III, intermediate 86-105 6.5%
Class IV, high 106-125 10.4%
Class V, very high > 125 24.5%

* With and without the supplemental oxygen. # Defined as disorientation, lethargy, stupor, or coma. Estimates in the derivation cohorts.

PESI, pulmonary embolism severity index; SBP, systolic blood pressure.