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Quantitative trait loci (QTL) analysis of lumefantrine phenotypes in the 803 × GB4 cross. A QTL plot from LUM 72 h half-maximal effective concentration (EC50) determinations. Maximal logarithm of odds (LOD) score is at location 966,290 on Chromosome 5 (p < 0.005). B QTL plot from the parasitemia Days to Recovery (DTR) LUM data, with a maximal LOD score at location 966,290 on Chromosome 5 (p < 0.005). Dashed lines in the figure panels mark the 0.05 significance threshold.
