Fig. 4.

Redox imbalance in FRDA fibroblasts. A) DNA damage evaluated by the γ-H2AX foci analysis (red) and telomere dysfunction-induced foci (TRF1) (green). On the right, the quantification of γ-H2AX and TRF1 foci in FRDA patient's fibroblasts. B) Immunofluorescence of GS-pro using the anti-GS-pro antibody specifically probing glutathionylated proteins (green). Hoechst staining was performed for nuclear staining (blue). Scale Bar = 100 μm. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)