Table 3. Adjusted Hazard Ratio for OS and BCSS Associated With Adjuvant Therapies After Different Surgical Procedures in Patients With Different Cancer Stages and Ages.
| Characteristic | BCS | Othera | ||||||
|---|---|---|---|---|---|---|---|---|
| Chemotherapy | Radiotherapy | Chemotherapy | Radiotherapy | |||||
| AHR (95% CI) | P Value | AHR (95% CI) | P Value | AHR (95% CI) | P Value | AHR (95% CI) | P Value | |
| Age | ||||||||
| <70 | ||||||||
| OS | 0.574 (0.400-0.824) | .003 | 0.977 (0.673-1.417) | .9 | 0.610 (0.395-0.941) | .03 | 2.514 (1.408-4.490) | .002 |
| BCSS | 0.812 (0.512-1.287) | .38 | 1.023 (0.651-1.608) | .92 | 0.835 (0.493-1.413) | .50 | 3.149 (1.708-5.805) | <.001 |
| ≥70 | ||||||||
| OS | 0.464 (0.305-0.704) | <.001 | 0.507 (0.349-0.736) | <.001 | 0.506 (0.268-0.954) | .04 | 1.324 (0.406-4.320) | .64 |
| BCSS | 1.252 (0.665-2.358) | .49 | 0.478 (0.251-0.913) | .03 | 0.940 (0.435-2.030) | .87 | 1.336 (0.309-5.774) | .70 |
| Stage | ||||||||
| T1ab | ||||||||
| OS | 0.533 (0.290-0.980) | .04 | 0.446 (0.254-0.782) | .005 | 1.159 (0.609-2.208) | .65 | 2.267 (0.980-5.243) | .06 |
| BCSS | 1.367 (0.565-3.307) | .49 | 0.469 (0.191-1.148) | .10 | 1.454 (0.661-3.200) | .35 | 2.786 (1.098-7.070) | .03 |
| T1c | ||||||||
| OS | 0.564 (0.419-0.760) | <.001 | 0.812 (0.606-1.088) | .16 | 0.416 (0.273-0.634) | <.001 | 2.240 (1.153-4.350) | .02 |
| BCSS | 0.821 (0.541-1.245) | .35 | 0.915 (0.613-1.366) | .66 | 0.579 (0.338-0.990) | .04 | 2.916 (1.432-5.938) | .003 |
Abbreviations: AHR, adjusted hazard ratio; BCS, breast-conserving surgery; BCSS, breast cancer-specific survival; OS, overall survival.
a
Other included patients receiving simple mastectomy, radical mastectomy, or other surgical procedures.