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. 2020 Nov 19;3(11):e2020161. doi: 10.1001/jamanetworkopen.2020.20161

Table 1. Demographic Characteristics, Frail Meter Parameters, and Risk Factors of Participants Undergoing Revascularization.

Characteristic Patients, No./total No. (%), by group P value
Robust (n = 53) Prefrail (n = 58) Frail (n = 41)
Demographic characteristics
Age, mean (SD), y 65.2 (11.5) 67.2 (11.8) 71.9 (11.2) .02
Women 17/53 (32.1) 22/57 (38.6) 20/41 (48.8) .26
Height, mean (SD), cm 165 (9) 167 (18) 165 (11) .40
Weight, mean (SD), kg 73.7 (13.3) 83.7 (27.1) 72.7 (19.7) .14
BMI, mean (SD) 27.3 (5.2) 28.7 (7.0) 26.5 (6.4) .47
Mobility aid 7/13 (53.8) 22/35 (62.9) 21/26 (80.8) .17
Race/ethnicity
White 18/53 (34.0) 23/57 (40.4) 14/41 (34.1) .26
African American 6/53 (11.3) 11/57 (19.3) 10/41 (24.4)
Hispanic or Latino 29/53 (54.7) 22/57 (38.6) 17/41 (41.5)
Asian 0 1/57 (1.8) 0
Peripheral artery disease risk factors
History of foot ulcer 8/13 (61.5) 29/36 (80.6) 17/26 (65.4) .28
Diabetes 11/13 (84.6) 31/36 (86.1) 22/26 (84.6) .98
Hypertension 33/53 (62.3) 19/58 (32.8) 12/41 (29.3) .001
Heart disease 17/53 (32.1) 25/58 (43.1) 15/41 (36.6) .48
Stroke 3/53 (5.7) 7/58 (12.1) 10/41 (24.4) .03
Renal disease 18/53 (34) 11/58 (19) 9/41 (22) .17
History of tobacco use 28/53 (52.8) 36/56 (64.3) 28/41 (68.3) .27
Prescription medications, mean (SD), No. 7.9 (4.0) 8.8 (4.2) 8.9 (4.1) .75
History of fall 3/11 (27.3) 6/30 (20.0) 12/23 (52.2) .04
Comorbidities, mean (SD), No. 3.2 (1.7) 2.8 (2.9) 3.0 (1.5) .57
Rutherford score, mean (SD) 5.3 (0.8) 5.3 (1.5) 5.2 (0.9) .97
Length of hospital stay, mean (SD), d 10.92 (7.75) 9.65 (16.52) 16.32 (20.41) .20
Type of intervention
Open 13/53 (24.5) 16/58 (27.6) 8/41 (19.5) .65
Endovascular 40/53 (75.4) 42/58 (72.4) 33/41 (80.5)
Frail meter parameters and phenotypes, mean (SD)a
Overall frailty index score 0.13 (0.05) 0.27 (0.04) 0.45 (0.08) <.001
Speed, ie, slowness, deg/s 1101 (364) 665 (210) 327 (176) <.001
Speed reduction, ie, exhaustion, % 10.74 (24.36) −3.38 (12.08) −15.03 (20.87) <.001
ROM, ie, flexibility, deg 107 (33) 80 (27) 40 (24) <.001
Power, ie, weakness, deg2/s3 x 105 2.63 (1.91) 0.84 (0.75) 0.23 (0.33) <.001
Flexion time, ms 336 (77) 425 (133) 600 (360) <.001
Flexions, No. 30 (8) 24 (8) 20 (9) <.001

Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); ROM, range of motion.

a

Associated Fried phenotypes were determined according to the study by Toosizadeh et al.16