Table 2. Virological data of human West Nile virus infection casesa, Leipzig, Germany, August–September 2020 (n = 9).
| Cases | Time to diagnosis (days)b | WNV IgM | WNV IgG | WNV RNA in urine (GE/mL) | WNV RNA in serum (GE/mL) | WNV RNA in CSF (GE/mL) | WNV cell-culture isolation | WNV lineage |
|---|---|---|---|---|---|---|---|---|
| Case 1 | 8 | Positive | Sero-conversion | Undetectable | Undetectable | Undetectable | ND | ND |
| Case 2 | 6 | Positive | Positive | 1,010,000 | 1,000 | Undetectable | Positive | 2 |
| Case 3 | 6 | Positive | Negativec | 500 | 200 | Undetectable | ND | 2 |
| Case 4 | 6 | Positive | Sero-conversion | 100 | Undetectable | Undetectable | ND | 2 |
| Case 5 | 6 | Positive | Positive | 6,450,000 | 150 | Undetectable | Positive | 2 |
| Case 6 | 7 | Positive | Sero-conversion | 67,200,000 | 5,200 | 1,500 | Positive | 2 |
| Case 7 | 8 | Positive | Positive | Undetectable | Undetectable | Undetectable | ND | ND |
| Case 8 | 5 | Positive | Sero-conversion | Undetectable | Undetectable | ND | ND | ND |
| Case 9 | 12 | Positive | Positive | Undetectable | Undetectable | ND | ND | ND |
CSF: cerebrospinal fluid; GE: genome equivalents; ND: not determined; WNV: West Nile virus.
a Five confirmed and four probable cases according to the European Union case definition [1].
b This is the time between symptom onset and the day of first sample collection.
c WNV IgG was still undetectable at the last day of follow-up (20 days after symptom onset).