Table 3.
Hazard Ratio (HR) and 95% confidence interval of nomogram parameters.
| HR (95% CI) | p-value | |
|---|---|---|
| Age | 1.01 (1.01-1.02) | < 0.001 |
| Sex (Female vs. Male) | 0.88 (0.85-0.9) | < 0.001 |
| Race | ||
| White | 1 (reference) | - |
| Black | 0.88 (0.84-0.92) | < 0.001 |
| Other | 0.89 (0.8-0.98) | 0.02 |
| Hispanic origin (Yes vs. No) | 0.75 (0.68-0.82) | < 0.001 |
| Charlson/Deyo score | ||
| 0 | 1 (reference) | - |
| 1 | 1.18 (1.14-1.21) | < 0.001 |
| >= 2 | 1.36 (1.31-1.41) | < 0.001 |
| AJCC V8 TNM stage | ||
| IA | 1 (reference) | - |
| IB | 1.17 (1.02-1.35) | 0.02 |
| IIA | 1.49 (1.2-1.84) | < 0.001 |
| IIB | 1.7 (1.52-1.9) | < 0.001 |
| IIIA | 2.04 (1.83-2.26) | < 0.001 |
| IIIB | 2.38 (2.11-2.68) | < 0.001 |
| IIIC | 2.97 (2.5-3.54) | < 0.001 |
| IVA | 3.86 (3.48-4.27) | < 0.001 |
| IVB | 5.62 (5.06-6.24) | < 0.001 |
| Treatment | ||
| No surgery, no chemo, no radiation | 1 (reference) | - |
| No surgery, no chemo, radiation done | 0.67 (0.63-0.71) | < 0.001 |
| No surgery, chemo done, no radiation | 0.35 (0.33-0.36) | < 0.001 |
| No surgery, chemo done, radiation done | 0.25 (0.24-0.26) | < 0.001 |
| Surgery done, no chemo, no radiation | 0.31 (0.28-0.35) | < 0.001 |
| Surgery done, no chemo, radiation done | 0.35 (0.27-0.46) | < 0.001 |
| Surgery done, chemo done, no radiation | 0.21 (0.19-0.23) | < 0.001 |
| Surgery done, chemo done, radiation done | 0.18 (0.17-0.2) | < 0.001 |
| Laterality | ||
| Not a paired site | 1 (reference) | - |
| Only one side involved | 0.95 (0.91-0.99) | 0.02 |
| Bilateral involvement | 0.72 (0.66-0.79) | < 0.001 |
| Paired site but lateral origin unknown; midline tumor | 1.05 (0.98-1.13) | 0.19 |