Table 1.

Methylation Level of Different CpG Sites Between Case and Control Groups

(A)
Group	CpG1	CpG2	CpG3	CpG4	CpG5
Case group	6.13±1.36	2.67±0.98	4.80±1.21	0.67±0.90	0.60±0.63
Control group	4.07±1.22	2.13±0.99	4.60±1.56	0.73±1.16	0.93±1.10
t	4.384	1.486	0.387	−0.176	−1.018
P	0.000*	0.149	0.701	0.862	0.320
Notes: P<0.05 represented the statistical significance between case and control group. *P<0.001.
(B)
Group	CpG6	CpG7	CpG8	CpG9	CpG10
Case group	0.40±0.74	1.80±1.15	0.27±0.46	2.33±1.11	0.07±0.26
Control group	0.47±0.92	1.47±1.30	0.60±1.06	1.93±0.88	0.20±0.56
t	−0.220	0.744	−1.122	1.090	−0.837
P	0.828	0.463	0.271	0.285	0.410
(C)
Group	CpG11	CpG12	CpG13	CpG14	CpG15
Case group	1.00±1.31	0.80±0.78	0.60±0.74	0.67±0.72	0.33±0.49
Control group	0.80±0.94	0.87±0.83	0.67±0.72	0.40±0.51	0.33±0.49
t	0.480	−0.227	−0.250	1.169	0.000
P	0.635	0.822	0.804	0.252	1.000
(D)
Group	CpG16	CpG17	CpG18	CpG19	CpG20
Case group	0.53±0.64	0.47±0.52	0.73±0.80	0.53±0.64	0.20±0.41
Control group	0.47±0.64	0.27±0.46	0.60±0.91	0.27±0.46	0.27±0.59
t	0.285	1.122	0.426	1.313	−0.357
P	0.778	0.271	0.673	0.201	0.724
(E)
Group	CpG21	CpG22	CpG23	CpG24
Case group	0.07±0.26	0.13±0.35	0.07±0.26	0.13±0.35
Control group	0.07±0.26	0.07±0.26	0.13±0.35	0.07±0.26
t	0.000	0.592	−0.592	0.592
P	1.000	0.559	0.559	0.559