Table 3.

LFQ (log2 transformed) of single proteins enriched in cardioembolic as compared to atherothrombotic thrombi.

Gene	Uniprot Identification (40)	Protein name	Main known protein function (40)	Subcellular Location	Student's T-test Difference Log2 LFQ intensity Atheroma_Log2 LFQ intensity Cardioembolic	-log P-value
SLC25A11	Q02978	Mitochondrial 2-oxoglutarate/malate carrier protein	Catalyzes the transport of 2-oxoglutarate at mitochondrial membrane	Mitochondrion	−1.278498	1.94
APOE	P02649	Apolipoprotein E	Lipid transport between organs via the plasma and interstitial fluids	Extracellular	−1.34310437	1.69
PHB	P35232	Prohibitin	Inhibits DNA synthesis	Mitochondrion	−1.1333107	2.46
ATP5A1	P25705	ATP synthase subunit alpha	Produces ATP from ADP	Mitochondrion, plasma membrane	−1.1749357	1.93