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. Author manuscript; available in PMC: 2021 Jan 14.
Published in final edited form as: Polym Chem. 2019 Oct 23;11(2):568–580. doi: 10.1039/c9py01206k

Table 3. Pseudo-first order rate constants for co-monomer formulations.

The table shows rate constants in units of inverse days for the four PEGDA-based nanoparticle formulations with co-monomers as well as for the 50 wt% formulation with no co-monomer in each of the three respective incubation conditions. The rate constants were determined assuming pseudo-first order kinetics.

Formulation
(NP)
50 wt% (Inline graphic) (days−1) 50 wt% with 10% HDDMA (Inline graphic) (days−1) 50 wt% with 30% HDDMA (Inline graphic) (days−1) 50 wt% with 10% DSDMA (Inline graphic) (days−1) 50 wt% with 30% DSDMA (Inline graphic) (days−1)
Degradation
Condition
pH 5 Condition 0.017 ± 0.003 0.699 ± 0.254 1.490 ± 0.345 0.669 ± 0.224 1.039 ± 0.560
pH 7.4 Condition 0.020 ± 0.006 0.357 ± 0.088 0.139 ± 0.171 0.547 ± 0.136 0.605 ± 0.174
pH 10 Condition 0.009 ± 0.002 0.167 ± 0.037 0.169 ± 0.123 0.031 ± 0.136 0.023 ± 0.130