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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: J Neuroophthalmol. 2020 Dec;40(4):514–519. doi: 10.1097/WNO.0000000000000971

Table 1:

Sensitivity, specificity, and positive and negative predictive values for ICD code-based definitions of neuro-ophthalmic conditions

Condition No. of studies No. of case definitions/validations Sensitivity (range) Specificity (range) PPV (range) NPV (range)
IIH 3 4 54–91% 74–85%
GCA 2 2 30–96% 94%
Optic neuritis 3 6 76–99% 83–100% 25–100% 98–100%
NMO 1 3 60% 100% 43–100% 100%
Cranial nerve palsy 1 3 98–99%
MG 2 6 53–97% 99–100% 5–90% 100%
NAION 0
TED 0
Blepharospasm 0