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. 2020 Nov 19;10:20211. doi: 10.1038/s41598-020-77057-3

Table 1.

Baseline data of subjects and white spot lesions.

Parameter Study population
Number of subjects 44
Age 27.1 (15–39) years
Sex

18 (41%) male

26 (59%) females

Ethnicity Caucasian 36 (82%)
Arabian 3 (7%)
African 3 (7%)
Indian 2 (4%)
DMFT 4.4 ± 5.1 (0–21)
Oral hygiene Poor 0
Unsatisfactory 3 (7%)
Sufficient 5 (11%)
Good 11 (25%)
Excellent 25 (57%)
Test lesions (n = 44) Control lesion (n = 44)
Plaque index 0.20 ± 0.25 (0–1.2)
Gingival index 0.08 ± 0.12 (0–1.2)
Clinical index white spot lesion*
0 0 (0%) 0 (0%)
1 2 (4%) 1 (2%)
2 7 (16%) 10 (23%)
3 18 (41%) 19 (43%)
4 17 (39%) 14 (32%)
Lesion appearance
Shiny 16 (36%) 17 (39%)
Opaque 28 (64%) 27 (61%)
Lesion texture
Smooth/hard 34 (77%) 34 (77%)
Rough/soft 10 (23%) 10 (23%)
Lesion location/origin
Far from sulcus 1 (2%) 2 (4%)
Close to sulcus 43 (98%) 42 (96%)
Post-orthodontic 0 (0%) 0 (0%)
Nyvad score
Active (Score 1, 2) 25 (57%) 30 (68%)
Inactive (Score 4, 5) 19 (43%) 14 (32%)
Laser fluorescence
Mean (SD) 6.7 ± 5.3 6.5 ± 4.9
Min 2 3
Median 5 5
Max 29 32
Counts (< 10: healthy) 40 (91%) 39 (89%)
Counts (≥ 10: caries) 4 (9%) 5 (11%)
Lesion size (morphometry/pixel) 53′023 ± 70′022 50′787 ± 69′584
Clinical phase (first patient in—last patient out) November 2013–January 2016

*0: No visible colour change, 1: Slight white colour change, only visible after air-drying, 2: Slight white colour change with certain marked white areas, 3: White consistent colour change, 4: Distinct white colour change.