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. 2020 Nov 19;10:20233. doi: 10.1038/s41598-020-75450-6

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Hypertension causes slower sensorimotor recovery. (A) Both strains had significant neurological impairment (Modified Bederson’s Score) starting 24 h after stroke and up to day 14. (n = 6–12 per group) (One sample t-test compared to the maximum score of 8). (B) There was no significant difference between the 4 groups in object discrimination in the novel object recognition test at 2- and 12-weeks post MCAO. (n = 6–12 per group). (C) SHRs showed a trend for reduced total object exploration time at 2-weeks post stroke (p = 0.058, 2-way ANOVA). The difference disappeared at 12-weeks post-stroke. (n = 6–12 per group).