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. 2020 Jun 23;15(12):1336–1347. doi: 10.1080/15592294.2020.1780081

Figure 3.

Figure 3.

The interaction network between proteins, each of which is involved in the regulation of immunity, apoptosis, and ageing (bold circles), which are also direct or indirect SIRT6 interactors. The network was constructed using the STRING functional protein association network version 10.5 (https://string-db.org/) with the minimum required interaction score of 0.4 (medium confidence). To fill ‘gaps’ between SIRT6 and these proteins, the program was allowed to include up to 5 additional interactors in the first shell