Table 3. List of B. pseudomallei proteins homologous to previously reported DsbA substrates.

Accession Number (DsbA substrate)	Organism	Reference	B. pseudomallei homologue	Identity / coverage (%)	Protein function	Cys #
WP_059237834	B. cepacia	[57]	WP_076835606.1	89 /100	Sulfatase like hydrolase /transferase	3
WP_006481898	B. cenocepacia	[58, 59]	WP_139900467	87/100	M4 family metallopeptidase	4
gi|89255876	F. tularensis	[43]	WP_050859308	24/92	lytic transglycosylase	3
gi|89255615	F. tularensis	[43]	WP_080367462	40/51	Pilin	2
gi|89255615	F. tularensis	[43]	WP_076953316	27/92	Pilin	2
gi|89256194	F. tularensis	[43]	WP_041862011	30/83	Molybdopterin synthase adenyl transferase (MoeB)	13
gi|89256236	F. tularensis	[43]	WP_064459078	34/53	DNA/RNA endonuclease	2
gi|89256237	F. tularensis	[43]	WP_050772403	31/90	PenI family β-lactamase	4
gi|89256856	F. tularensis	[43]	WP_044360358	21/80	hypothetical protein	4
gi|89256859	F. tularensis	[43]	WP_058035453	39/80	Polyamine ABC transporter substrate binding protein	3
gi|89257049	F. tularensis	[43]	WP_009915682	54/99	Succinate dehydrogenase	6
WP_001363619	E. coli	[31]	WP_102811167	38/88	Molecular chaperone	3
AAC38377	E. coli	[31]	WP_082252625	44/93	T3SS outer membrane ring protein	4
AAA24962	Heamophilus Influenza	[31]	WP_053293022	47/92	ABC transporter substrate binding protein	4
CAA43967	Yersinia pestis	[31]	WP_085538626	32/83	Pilus assembly protein PapD	2

The accession number of the known DsbA substrate (in an organism other than B. pseudomallei), the organism and the publication reference are given in the first three columns. The corresponding B. pseudomallei homologue is given in the fourth column. The identity and coverage (number of residues in the result sequence that overlap with the search sequence) is given in percent in the column “identity/coverage”. The final two columns provide the protein function and the number of cysteines in the predicted mature sequence. All proteins in this table are known or predicted to be secreted or periplasmic.