Table 1. Characteristics of participants, 12-year verbal fluency decline and volumetric variables.
| Sample n = 68 | |
|---|---|
| Sociodemographic variables | Mean ± SD or % |
| Age | 81.2 ± 0.48 |
| Male gender | 36.8% |
| High level of education | 37% |
| Clinical variables | |
| MMSE | 27.3 ± 0.3 |
| CES-D | 8.3 ± 0.9 |
| BMI (kg/m2) | 25.2 ± 0.5 |
| Diabetes | 10.3% |
| Hypertension | 35.3% |
| Verbal fluency decline | |
| IST at 15 seconds | -0.489 ± 0.02 |
| IST at 30 seconds | -0.697 ± 0.04 |
| IST at 60 seconds | -0.924 ± 0.06 |
| Volumetric variables | |
| Total WMH volume ml | 15.9 ± 4.1 |
| Cingulum bundle volume (% TIV) | 0.46 ± 0.06 |
| Cingulum WMH volume (%) | 3.2 ± 0.65 |
MMSE, Mini Mental State Examination; BMI, Body Mass Index; CES-D, Center for Epidemiologic Studies-Depression scale; IST, Isaacs Set Test; WMH, White Matter Hyperintensity.