Table 3. Correlations between cingulum diffusion measures and verbal fluency score (IST) before (conventional DTI) and after FW-correction.
DTI | |||||||
IST 15s | IST 30s | IST 60s | |||||
β | R2 | β | R2 | β | R2 | ||
Model unadjusted for total WMH | FA | 0.015 | 0.001 | 0.047 | 0.002 | 0.067 | 0.004 |
MD | -0.421* | 0.17 | -0.335* | 0.12 | -0.174 | 0.07 | |
AD | -0.186 | 0.036 | -0.135 | 0.018 | -0.060 | 0.004 | |
RD | -0.114 | 0.013 | -0.128 | 0.016 | -0.129 | 0.017 | |
FW-corrected | |||||||
IST 15s | IST 30s | IST 60s | |||||
β | R2 | β | R2 | β | R2 | ||
Model unadjusted for total WMH | FAt | 0.047 | 0.003 | 0.098 | 0.01 | 0.095 | 0.009 |
MDt | -0.443* | 0.19 | -0.361* | 0.13 | -0.226 | 0.08 | |
ADt | -0.198 | 0.04 | -0.134 | 0.018 | -0.061 | 0.004 | |
RDt | -0.293* | 0.11 | -0.248* | 0.13 | -0.199 | 0.039 | |
FW | -0.353* | 0.12 | -0.241* | 0.10 | -0.196 | 0.061 |
β, standardized coefficient regression adjusted for age and cingulum white matter volume
R2, R square value
* p < 0.05 FDR corrected