Table 1. AURKA mRNA expression level in BC compared to normal tissues (Oncomine) in 12 datasets.
BC Subtype | Fold-change | P-value | Rank (%) | Sample | Source |
---|---|---|---|---|---|
Ductal BC | 9.423 | 1.18 × 10-14 | 1 | 47 | (Richardson et al., 2006) |
Medullary BC | 4.706 | 7.88 × 10-19 | 1 | 2136 | (Curtis et al., 2012) |
Invasive Ductal BC | 3.168 | 4.88 × 10-120 | 1 | 2136 | (Curtis et al., 2012) |
Invasive Lobular BC | 2.115 | 5.80 × 10-44 | 2 | 2136 | (Curtis et al., 2012) |
Invasive Ductal & Invasive Lobular BC | 2.339 | 1.02 × 10-31 | 2 | 2136 | (Curtis et al., 2012) |
Invasive BC | 2.586 | 9.96 × 10-7 | 3 | 2136 | (Curtis et al., 2012) |
Mucinous BC | 2.137 | 8.28 × 10-16 | 3 | 593 | TCGA, 2011 |
Invasive Ductal BC | 4.702 | 5.39 × 10-53 | 1 | 593 | TCGA, 2011 |
Invasive BC | 3.468 | 5.83 × 10-26 | 1 | 593 | TCGA, 2011 |
Invasive Lobular BC | 2.351 | 7.20 × 10-14 | 2 | 64 | TCGA, 2011 |
Invasive Ductal BC | 2.154 | 2.34 × 10-7 | 4 | 64 | (Zhao et al., 2004) |
Invasive Breast Carcinoma Stroma | –11.071 | 2.11 × 10-30 | 2 | 59 | (Finak et al., 2008) |
Notes: P-value was analyzed using the t-test. The P-values indicate that the difference was statistically significant between the BC and normal tissue group. Abbreviations: BC, breast carcinoma. mRNA levels of AURKA in different subtypes of BC.