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. 2020 Nov 17;11(46):4306–4324. doi: 10.18632/oncotarget.27811

Table 1. AURKA mRNA expression level in BC compared to normal tissues (Oncomine) in 12 datasets.

BC Subtype Fold-change P-value Rank (%) Sample Source
Ductal BC 9.423 1.18 × 10-14 1 47 (Richardson et al., 2006)
Medullary BC 4.706 7.88 × 10-19 1 2136 (Curtis et al., 2012)
Invasive Ductal BC 3.168 4.88 × 10-120 1 2136 (Curtis et al., 2012)
Invasive Lobular BC 2.115 5.80 × 10-44 2 2136 (Curtis et al., 2012)
Invasive Ductal & Invasive Lobular BC 2.339 1.02 × 10-31 2 2136 (Curtis et al., 2012)
Invasive BC 2.586 9.96 × 10-7 3 2136 (Curtis et al., 2012)
Mucinous BC 2.137 8.28 × 10-16 3 593 TCGA, 2011
Invasive Ductal BC 4.702 5.39 × 10-53 1 593 TCGA, 2011
Invasive BC 3.468 5.83 × 10-26 1 593 TCGA, 2011
Invasive Lobular BC 2.351 7.20 × 10-14 2 64 TCGA, 2011
Invasive Ductal BC 2.154 2.34 × 10-7 4 64 (Zhao et al., 2004)
Invasive Breast Carcinoma Stroma –11.071 2.11 × 10-30 2 59 (Finak et al., 2008)

Notes: P-value was analyzed using the t-test. The P-values indicate that the difference was statistically significant between the BC and normal tissue group. Abbreviations: BC, breast carcinoma. mRNA levels of AURKA in different subtypes of BC.