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. Author manuscript; available in PMC: 2020 Nov 20.
Published in final edited form as: ACS Appl Bio Mater. 2020 Apr 22;3(5):2930–2939. doi: 10.1021/acsabm.9b01198

Figure 2. In vivo Intramyocardial delivery of ICAM1 antibody-coated MSCs in infarcted mouse model.

Figure 2.

(a) Timeline of MI induction, MSC injection and sample collection. The coated or uncoated cells were directly injected into peri-infarct area 2 hour after left anterior descending artery ligation. At day 3, the heart sample was collected and digested for flow cytometry and immunohistochemistry analysis. (b) Representative immunofluorescent analysis of uncoated and anti-ICAM1 coated GFP-MSCs retention in infarcted heart tissues. The scale bar is 20 μm. (c) Quantitative retention analysis of uncoated MSCs (n=4) and anti-ICAM1-coated MSCs (n=3) through flow cytometry.