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. 2020 Nov 20;15(11):e0242400. doi: 10.1371/journal.pone.0242400

Table 3. Multivariable models to identify predictors of mortality in hospitalized COVI19 patients.

Model 1* Variable OR 95% CI p
Age 1.069 1.032–1.108 <0.001
CRP Slope d1to7 1.03 1.014–1.046 <0.001
CRP tests (count d1 to 7) 0.55 0.386–0.785 0.001
CRRT 4.379 1.844–10.395 0.001
CRP Max d1to7 1.007 1.003–1.011 0.001
Obesity (BMI> = 30kg/m2) 0.341 0.147–0.792 0.012
Intubation 4.435 1.007–19.527 0.049
SOFA score 1.038 0.93–1.159 0.506
CAD 1.381 0.498–3.826 0.535
Hypertension 1.142 0.44–2.964 0.785
Model 2# Variable OR 95% CI p
Age 1.066 1.032–1.102 <0.001
CRRT 4.994 2.17–11.491 <0.001
CRP tests (count d1 to 7) 0.621 0.464–0.83 0.001
CRP Slope d1to7≥10 2.98 1.437–6.181 0.003
Intubation 4.237 1.176–15.258 0.027
Obesity (BMI≥30kg/m2) 0.437 0.2–0.956 0.038
MaxCRP d1to7 ≥250 2.221 0.997–4.948 0.051
CAD 1.6 0.625–4.1 0.327
Hypertension 1.13 0.455–2.809 0.792
SOFA score 1.004 0.905–1.114 0.938

*Model 1: CRP slope and Maximum CRP levels during the first 7 days were used as continuous variables in the model.

#Model 2: CRP slope≥0 and Maximum CRP level≥250 were used as thresholds in the model.