. 2020 Nov 20;15(11):e0242671. doi: 10.1371/journal.pone.0242671

Table 6. Analysis of agreement between official and bed-side diagnostics of low muscle mass, sarcopenia, obesity and sarcopenic obesity.

Low Muscle Mass			Sarcopenia			Obesity			Sarcopenic Obesity
Bed-side diagnostic	Female	Male	Bed-side diagnostic	Female	Male	Bed-side diagnostic	Female	Male	Bed-side diagnostic	Female	Male
Low pFFM	0.76^*	0.77^*	Low pFFM + Low HGS	0.81^*	0.81^*	High pFMI	0.77^*	0.83^*	High pFMI + Low pFFM	0.69^*	0.78^*
Low AFFM	0.82^*	0.76^*	Low AFFM + Low HGS	0.86^*	0.80^*	High FMIBCM	0.83^*	0.77^*	High pFMI + Low AFFM	0.74^*	0.75^*
Low CC	0.64^*	0.53^*	Low CC + Low HGS	0.71^*	0.59^*	High WC/H	0.60^*	0.67^*	High FMIBCM+ Low pFFM	0.73^*	0.73^*
									High FMIBCM+ Low AFFM	0.78^*	0.71^*

*Kappa coefficient of agreement between official and bed-side diagnostic, p≤0.05. Official low muscle mass diagnostic: for women, ALM<15kg; for men, ALM<20kg [10]. Official sarcopenia diagnostic: for women, ALM<15kg and HGS<16kg; for men, ALM<20kg and HGS<27kg [10]. Official obesity diagnostic: for women, FMI>13kg/m²; for men, FMI>9kg/m²[14]. Official sarcopenic obesity: for women, ALM<15kg and FMI>13kg/m²; for men, ALM<20kg and FMI>9kg/m². For official diagnostics, body composition measures were performed with dual energy X-ray absorptiometry. Bed-side low muscle mass diagnostic: for women, pFFM≤35.02kg, AFFM≤15.87kg and CC≤35.5cm; for men, pFFM≤46.42kg, AFFM≤21.43kg and CC≤37cm. Bed-side sarcopenic diagnostic: for women, pFFM≤35.02kg and HGS<16kg, AFFM≤15.87kg and HGS<16kg, CC≤35.5cm and HGS<16kg; for men, pFFM≤46.42kg and HGS<20kg, AFFM≤21.43kg and HGS<20kg, CC≤37cm and HGS<20kg. Bed-side obesity diagnostic: for women, pFMI>12.20kg/m², FMIBCM>12.58kg/m² and WC/H>0.66; for men, pFMI>8.76kg/m², FMIBCM>8.82kg/m² and WC/H>0.60. Bed-side sarcopenic obesity: for women, pFMI>12.20kg/m² and AFFM≤15.87kg, FMIBCM>12.58kg/m² and pFFM≤35.02kg, FMIBCM>12.58kg/m² and AFFM≤15.87kg; for men, pFMI>8.76kg/m² and pFFM≤46.42kg, pFMI>8.76kg/m² and AFFM≤21.43kg, FMIBCM>8.82kg/m² and pFFM≤46.42kg, FMIBCM>8.82kg/m² and AFFM≤21.43kg. AFFM, appendicular fat free mass; ALM, appendicular lean mass; CC, calf circumference; FMIBCM, fat mass index body composition monitor; HGS, hand grip strength; pFFM, predicted fat free mass; pFMI, predicted fat mass index. pFFM, AFFM, pFMI and FMIBCM data by bioelectrical impedance analysis. AFFM by Sergi equation [20]. pFFM and pFMI by Bellafronte equation [22]. FMIBCM by bioelectrical impedance from body composition monitor (Fresenius Medical Care).