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. Author manuscript; available in PMC: 2020 Nov 20.
Published in final edited form as: Annu Rev Biomed Eng. 2019 Jun 4;21:325–364. doi: 10.1146/annurev-bioeng-092618-020341

Figure 3:

Figure 3:

Stereolithography (SL)-printed microfluidic devices. (a) A 3D micromixer created by digital light projection (DLP)-SL, the first 3D-printed microfluidic device. (b) A gradient generator, the first microfluidic device printed with a commercial desktop printer. (c) A 3D chaotic mixer SL-printed in poly(ethylene glycol) diacrylate with a molecular weight of 258 (PEG-DA-258), a transparent biocompatible resin. (d) Microneedles for transdermal drug delivery SL-printed in the biocompatible resin Ormocer. (e) Modular microfluidic platform. (f) An SL-printed droplet generator with coaxial architecture (top) in which monodisperse oil droplets are formed (bottom). (g) Coil-shaped microfluidic channel. (h) Examples of SL-printed connectors: a male barb (left) and a Luer connector (right). (i) Bioreactor for bacterial culture. (j) Microvalve printed in PEG-DA-258. (k) Microfluidic switch printed in Watershed. (l) Array of Quake-style microvalves printed in PEG-DA-258. (m) SL-printed valves that are torque actuated by hand. (n) Flexible structures and cytocompatible microchannels printed in a poly(dimethyl siloxane) (PDMS)-like resin. (o) Multimaterial microfluidic perfusion channels incorporating biotinylated glyceryl-dimethacrylate microstructures. (p) PEG-DA-700 hydrogel barriers coprinted between and within PEG-DA-258 microchannels. Panel a adapted from Reference 50 with permission from the Royal Society of Chemistry (RSC). Panel b adapted from Reference 51 with permission from the RSC. Panel c adapted from Reference 258 courtesy of A. Kuo and A. Folch. Panel d adapted from Reference 68 with permission from Wiley. Panel e adapted from Reference 70 with permission from the RSC. Panel f adapted from Reference 74 under a Creative Commons license (CC-BY-4.0). Panel g adapted from Reference 45 courtesy of A. Au and A. Folch. Panel h courtesy of A. Au and A. Folch. Panel i adapted from Reference 89 with permission from R.A. Britton. Panel j adapted from Reference 109 with permission from the RSC. Panel k adapted from Reference 110 courtesy of A. Au and A. Folch. Panel l adapted from Reference 113 courtesy of Y.-S. Lee and A. Folch. Panel m adapted from Reference 114 with permission from the American Chemical Society. Panel n adapted from Reference 115 courtesy of N. Bhattacharjee and A. Folch. Panel o adapted from Reference 126 with permission from S. Turri. Panel p adapted from Reference 121 courtesy of Y.T. Kim and A. Folch.