Table 1.
Review of studies reporting disseminated white matter microhemorrhages during COVID-19 outbreak
| Author | Study area | Number of cases | Hypotheses raised |
|---|---|---|---|
| Radmanesh [1] | New York (monocentric) | 7 | Hypoxemia/small vessel vasculitis |
| Kremer [2] | France (multicentric) | 9 | Hypoxemia/small vessel vasculitis |
| Vattoth [3] | Qatar (monocentric) | 1 | Hypoxemia |
| Chougar [4] | Paris (monocentric) | 8 | ECMO/anticoagulation overdose/microangiopathy |
| Klironomos [5] | Stockholm (monocentric) | 23 | Hypoxemia/microangiopathy/endothelial injury/ECMO |
| Lin [6] | New York [2hospitals] | 3 | Mechanical ventilation |
| Paterson [7] | UK (multicentric) | 4 | Endothelial injury |
| Fitsiori [8] | Geneva (monocentric) | 9 | Endothelial injury related to SARS-CoV-2/microangiopathy/ECMO/Hypoxemia/disseminated intravascular coagulation/hypercoagulable state |
| Freeman [9] |
Philadelphia (monocentric) |
4 | Thrombotic microangiopathy/hypoxemia |