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. 2020 Nov 20;3:699. doi: 10.1038/s42003-020-01432-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — Glial granules assembled from Tudor protein scaffold and other germ cell proteins, including Vasa, Polar granule component, and Piwi, function in brain transcriptome regulation. Evolutionarily conserved Piwi/Dpn-positive cells have been identified in the adult Drosophila brain and show remarkably long extensions which may be involved in signal transmission caused by aging, memory formation, or perturbations in the brain milieu such as pathogen invasion.