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. 2020 Nov 20;11(11):994. doi: 10.1038/s41419-020-03199-x

Fig. 3. The effect of FATP2 inhibitor on fibrotic kidney.

Fig. 3

a Representative images of FATP2 inhibitor presence or absence in healthy and UUO mouse kidney sections stained with HE, MTS, PAS staining. Schematic representation of tubular damage score and collagen positive area. Scale Bar: 100 μm. b Fibronectin, collagen-1, α-SMA, and GAPDH protein expression by immunoblot analysis in mouse kidney. GAPDH sets as loading control. Schematic representation of quantitative data of indicated proteins. c Fibronectin and α-SMA mRNA expression by RT-qPCR analysis. d Contents of total cholesterol, triglycerides, and free fatty acids in peripheral blood of mice. e Total fatty acids in mouse kidney (mean ± SEM). n = 6 mice. *P < 0.05, ns means no statistical significance.