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. 2020 Sep 12;28(11):1374–1382. doi: 10.1016/j.jsps.2020.09.001

Table 1.

The Variables for venlafaxine HCl FDOF formulae in 33 factorial design.

Independent Variables (Factors)
Low (−1) Middle (0) High (+1)
X1: Hyroxypropylmethylcellulose: (HPMC E3)(%) 2 3.5 5
X2: Sodium Starch Glycolate: (SSG) (%) 0 2.5 5
X3: Glycerol (%) 0 1.5 3
Dependent Variable (Response):
Y1: Disintegration Time (sec)
Y2: Swelling Index (%)
Y3: % Dissolution Efficiency (DE% 15) After 15 Min