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. 2020 Sep 12;28(11):1374–1382. doi: 10.1016/j.jsps.2020.09.001

Table 5.

Venlafaxine HCl FDOF optimized formula composition, predicted and observed responses.

Optimized formula composition Response (Y)
Predicted Observed
HPMC (X1): 2% w/w Disintegration time (Y1) 30.72 s 33.67 ± 2.08
SSG (X2): 5% w/w Swelling index: (Y2) 4.40 3.58 ± 0.50
Glycerol (X1): 1% w/w DE%15 (Y3) 65.16% 72.33 ± 3.17