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Tgel of PF127 formulations with different concentrations of PEG400, AuNPs-CLRE and AuNPs-HLRE, n = 3.
| Formulation code | PF127, % w/v | PEG 400, %w/w | DsiRNA-AuNPs (CLRE), mg/mL | DsiRNA-AuNPs (HLRE), mg/mL | Tgel (°C) |
|---|---|---|---|---|---|
| F1 (blank) | 25 | – | – | – | 24 ± 1 |
| F2 | 25 | 5 | – | – | 27 ± 1 |
| F3 | 25 | 10 | – | – | 30 ± 1 |
| F4 | 25 | 15 | – | – | 33 ± 1 |
| F5 | 25 | 22 | – | – | 37 ± 1 |
| F6 | 25 | 22 | 0.060 | – | 28 ± 1 |
| F7 | 25 | 22 | 0.125 | – | 26 ± 1 |
| F8 | 25 | 22 | 0.250 | – | 27 ± 1 |
| F9 | 25 | 22 | – | 0.060 | 32 ± 1 |
| F10 | 25 | 22 | – | 0.125 | 29 ± 1 |
| F11 | 25 | 22 | – | 0.250 | 27 ± 0 |
