Table 3.

Comparison of exposure measures by other methods.

	Standard view	Phys 1	Phys 2	Phys 3	Exposed Rmax = 6.5 Å	Exposed Rmax = 10.0 Å	Exposed Rmax = 4.5 Å	Not in contact with hydro-phobic core	(Moel-bert et al.	Semanta et al. [22] A	(Semanta et al. [22]) B
LYS	+/−	+1.8	−1.5	−3.0	5.9	5.6	7.3	+2.0	0.61	9.8	85
GLU	+/−	+1.6	−0.74	−2.5	5.4	5.5	6.0	+1.9	0.59	10.6	64
ARG	+/−	+1.0	−2.5	−3.0	5.1	4.6	6.5	+0.9	0.54	16.3	77
ASP	+/−	+2.4	−0.1	−2.5	5.1	5.3	5.1	+2.1	0.61	11.0	48
ASN	P	+0.4	−0.8	0	5.1	5.7	5.4	−0.3	0.57	12.0	48
HIS	+/− P	+1.4	−0.4	0	4.5	4.5	5.8	−0.05	0.42	15.2	47
GLN	P	+0.2	−0.8	0	4.4	4.3	5.8	−0.3	0.57	12.8	60
PRO	H	−0.3	+0.12	+1.4	4.2	4.4	4.9	−1.8	0.50	10.6	43
THR	P	+0.1	0	+0.4	4.0	4.4	4.3	−0.5	0.48	11.3	36
SER	P	+0.3	−0.2	−0.3	3.8	4.5	4.1	−0.2	0.57	9.3	28
TYR	P,H	+0.2	0	+2.3	3.6	3.2	5.1	−1.2	0.32	20.6	40
TRP	H	−0.2	+0.8	+3.4	3.2	3.0	4.5	−1.4	0.28	24.8	38
GLY	–	+1.1	+0.5	0	3.2	3.5	4.2	0	0.59	–	–
LEU	H	−0.7	+1.5	+1.8	3.2	3.0	5.6	−1.2	0.32	14.8	23
VAL	H	−0.5	+1.8	+1.5	2.7	3.1	4.2	−1.0	0.31	12.8	19
ILE	H	−0.8	+1.4	+1.8	2.7	2.6	4.5	−1.25	0.27	15.3	21
PHE	H	−0.6	+1.2	+2.5	2.7	2.3	5.0	−1.3	0.29	20.0	25
ALA	H	+0.3	+0.6	+0.5	2.6	3.3	3.8	−0.6	0.40	7.2	18
MET	H	−0.4	+0.6	+1.3	2.3	1.6	5.5	−1.0	0.37	16.5	29
CYS	H	+0.2	+0.3	+1.0	2.1	2.7	3.5	−0.5	0.27	13.4	10