Figure 7.

A: Random blood glucose concentrations after islet transplantation in KINGS male mice. All mice reach normoglycemia by 42 days posttransplantation and remain normoglycemic for at least 3 weeks. B: Weight monitoring after islet transplantation in KINGS male mice. C and D: Glucose-stimulated insulin secretion and islet insulin content for KINGS males and cured KINGS males after 8 weeks of subcapsular islet transplantation. Cured KINGS males have significant recovery of 20 mmol/L glucose-induced insulin secretion and insulin content compared with nontransplanted KINGS males. *P < 0.05, two-way ANOVA, n = 6–7 (C), *P < 0.05, unpaired t test, n = 5–14 (D).