Table 2. Comparison of postoperative variables in groups with strong responders and weak responders.
| 1 year follow up variables | Strong responders, n = 59a | Weak responders, n = 30a |
|---|---|---|
| UPDRS Ib | 2.2 (2.2) | 4.5 (4.0)f |
| UPDRS I changec | 0.4 (1.9) | 1.5 (1.7)f |
| UPDRS IIb | 8.4 (4.7) | 12.3 (6.1)f |
| UPDRS II changec | −2.8 (6.3) | 5.6 (5.9)f |
| UPDRS III, on-medb | 13.9 (7.5) | 21.5 (11.9)f |
| UPDRS III changec | −11.9 (11.6) | 7.3 (8.5)f |
| UPDRS III, off-medd | 20.9 (13.1) | 25.7 (6.7) |
| UPDRS III changee | −29.0 (13.8) | −12.4 (14.4)f |
| UPDRS IVb | 2.4 (2.2) | 3.5 (2.6)f |
| UPDRS IV changec | −4.1 (3.6) | 0.1 (4.2)f |
| Fluency total categoriesb | 33.8 (10.4) | 33.4 (8.5) |
| Fluency total lettersb | 31.2 (11.5) | 31.8 (12.8) |
| Stroop interferenceb | 75.6 (66.4) | 79.0 (55.7) |
| LEDD | 622 (511) | 717 (501) |
| LEDD change | −509 (472) | −577 (529) |
| LEDD change (%) | −40.7 (37.5) | −42.2 (35.2) |
| TEED | 145 (151) | 112 (69) |
Notes.
- LEDD
- levodopa equivalent daily dosage
- off-/on-med
- off-/on-medication
- off-/on-stim
- off-/on-stimulation
- TEED
- total electrical energy delivered
- UPDRS
- Unified Parkinson Disease Rating Scale
a
Mean (standard deviation)
b
On-stimulation, on-medication at one-year follow up
c
Difference between on-medication and on-stimulation vs. preoperative on-medication
d
On-stimulation and off-medication at one-year follow up
e
Difference between on-stimulation and off-medication vs. preoperative off-medication
f
Significant difference with p-value < 0.05, calculated with Mann Whitney-U test