Table 5.
Liver Toxicity 48 Hours and One Month After TACE Session
| DEB-TACE | c-TACE | +HA (n=32) |
–HA (n=29) |
p-value | |||||
|---|---|---|---|---|---|---|---|---|---|
| +HA (n=23) |
–HA (n=19) |
p-value | +HA (n=9) |
–HA (n=10) |
p-value | ||||
| Liver toxicity 48 h after TACE | |||||||||
| Bilirubin (grade 1/2) |
5/6 | 5/4 | 0.904 | 3/2 | 3/3 | 0.929 | 8/8 | 8/7 | 0.974 |
| AST (grade 1/2/3/4) |
6/3/9/2 | 5/2/1/0 | 0.011 | 0/2/5/1 | 3/0/0/0 | 0.004 | 6/5/14/3 | 8/2/1/0 | <0.001 |
| ALT (grade 1/2/3/4) |
8/1/8/0 | 5/1/0/0 | 0.012 | 3/3/0/1 | 0/0/0/0 | 0.006 | 11/4/8/1 | 5/1/0/0 | <0.001 |
| Liver toxicity one month after TACE | |||||||||
| Bilirubin (grade 1/2) |
8/2 | 5/2 | 0.788 | 4/0 | 1/1 | 0.209 | 12/2 | 6/3 | 0.339 |
| AST (grade 1/2/3/4) |
6/0/0/0 | 5/1/0/0 | 0.552 | 1/0/0/0 | 2/0/0/0 | 0.500 | 7/0/0/0 | 7/1/0/0 | 0.545 |
| ALT (grade 1/2/3/4) |
4/0/0/0 | 2/0/0/0 | 0.668 | 0/0/0/0 | 1/0/0/0 | 0.500 | 4/0/0/0 | 3/0/0/0 | 1.000 |
Abbreviations: +HA, concurrent chemoembolization of hepatic and EHC tumor feeding arteries; –HA, chemoembolization of only extrahepatic tumor feeding arteries; ALT, alanine transaminase; AST, aspartate transaminase; cTACE, conventional transarterial chemoembolization; DEB-TACE, drug-eluting beads transarterial chemoembolization; TACE, transarterial chemoembolization.