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. 2020 Nov 20;10:20276. doi: 10.1038/s41598-020-77332-3

Table 2.

Factors associated with HCC by multivariate logistic regression.

Variable HCC versus CH
(n = 107) versus (n = 159)
HCC versus LC
(n = 107) versus (n = 99)
HCC versus CH + LC
(n = 107) versus (n = 258)
OR SE p OR SE p OR SE P
Gender (Male/female) 19.288 0.995 0.003 5.612 0.844 0.041 14.364 0.906 0.003
Age (years) 1.137 0.032  < 0.0001 1.061 0.030 0.047 1.100 0.024  < 0.0001
HBV DNA (IU/mL, log) 0.656 0.234 0.072 0.619 0.210 0.022 0.672 0.163 0.015
ALT (IU/L) 0.996 0.004 0.243 0.999 0.005 0.767 0.997 0.003 0.303
AST (IU/L) 1.003 0.004 0.421 1.002 0.003 0.570 1.002 0.002 0.388
TBIL (μmol/L) 0.997 0.003 0.330 1.002 0.005 0.687 1.000 0.003 0.979
Albumin (g/L) 0.995 0.061 0.930 0.909 0.043 0.026 0.942 0.038 0.120
PTX3 (ng/mL) 1.639 0.097  < 0.0001 1.671 0.104  < 0.0001 1.617 0.075  < 0.0001
AFP (ng/mL) 1.001 0.0002 0.014 1.003 0.002 0.193 1.001 0.0002 0.002

HBV hepatitis B virus, HCC hepatocellular carcinoma, ALT alanine aminotransferase, AST aspartate aminotransferase, TBIL total bilirubin, PTX3 pentraxin 3, AFP α-fetoprotein, CH chronic hepatitis, LC liver cirrhosis.