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. 2020 Nov 20;6:35. doi: 10.1038/s41531-020-00136-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — These are box and whiskers plots (centre line: median, bounds of box: 25th and 75th percentile and whisker: 10th and 90th percentile) of MDS-UPDRS III, MDS-UPDRS IV, MDS-UPDRS Total, mBKS, Percent time over target (PTOT) and PDQ39 of the first and last visit in the PKG+ arm (white, first visit and light grey, last visit) and PKG− arm (dark grey, first visit and black, last visit) of cases reported as being out of target because of bradykinesia at the first visit. *, ** and *** indicate P < 0.05, P < 0.01 or P < 0.001, respectively, and n.s. indicates not significant (P > 0.05). The plot shows a significant reduction in all parameters in the PKG+ scores at last visit.