Table 3.

Associations Between Sleep Duration and Hs-CRP Levels in the Complete Samples

Model	≤6h		7h		8h	≥9h
	β(95% CI)	P value	β(95% CI)	P values	[Reference]	β(95% CI)		P value
Participants, No.	831		1575		3893	1871
Unadjusted	0.0957(0.0506, 0.1408)	<0.0001	0.0451(0.0098, 0.0803)	0.0122	[Reference]	0.0524(0.0192, 0.0856)		0.0020
Model 1a	0.0139(−0.0291, 0.0570)	0.5258	0.0064(−0.0268, 0.0397)	0.7051	[Reference]	0.0444(0.0131, 0.0757)		0.0054
Model 2 b	0.0153(−0.0281, 0.0588)	0.4896	0.0093(−0.0242, 0.0428)	0.5859	[Reference]	0.0421(0.0105, 0.0737)		0.0090
Model 3c	0.0094(−0.0341, 0.0528)	0.6722	0.0080(−0.0254, 0.0414)	0.6388	[Reference]	0.0396(0.0082, 0.0709)		0.0134
Model 4d	−0.0044(−0.0466, 0.0379)	0.8396	0.0081(−0.0224, 0.0406)	0.6247	[Reference]	0.0369(0.0062, 0.0676)		0.0183
Model 5e	−0.0049(−0.0472, 0.0373)	0.8194	0.084(−0.0241, 0.0409)	0.6113	[Reference]	0.0356(0.0050, 0.0663)		0.0228

Notes: Hs-CRP was normalized by natural-log transformation; the level of hs-CRP at eight hours of sleep was used as a reference. β (95% CI): Regression coefficients and 95% confidence interval of log hs-CRP across sleep duration categories. ^aModel 1 adjusted for age, sex, body mass index (BMI). ^bModel 2 adjusted for Model 1, educational attainment, geographical region, residence and household income per capita. ^cModel 3 adjusted for Model 2, smoking status, alcohol drinking habits, physical activities levels and total energy intake. ^dModel 4 adjusted for Model 3, systolic and diastolic blood pressure, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides, uric acid, fasting serum glucose, fasting serum insulin. ^eModel 5: adjusted for Model 4 and health status related variables (the histories of diagnosed diabetes, hypertension, myocardial infarction, stroke and cancer, the uses of oral antidiabetic medicines, insulin, and antihypertensive drugs).

Abbreviations: CI, confidence interval; hs-CRP, high-sensitivity C-reactive protein.