Table 5.
Relationships Between Sleep Duration and Hs-CRP Levels by Geographical Region
| Model | ≤6h | 7h | 8h | ≥9h | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| β(95% CI) | P value | β(95% CI) | P value | [Reference] | β(95% CI) | P value | ||||
| Southern Region | ||||||||||
| Participants, No. | 425 | 873 | 2201 | 1184 | ||||||
| Unadjusted | 0.1067(0.0432, 0.1703) | 0.0010 | 0.0421(−0.0059, 0.0901) | 0.0853 | [Reference] | 0.0417(−0.0015, 0.0849) | 0.0586 | |||
| Model 1a | 0.0018(−0.0583, 0.0620) | 0.9523 | −0.0032(−0.0480, 0.0417) | 0.8902 | [Reference] | 0.0207(−0.0197, 0.0611) | 0.3154 | |||
| Model 2 b | 0.0038(−0.0566, 0.0641) | 0.9025 | −0.0020(−0.0470, 0.0429) | 0.9292 | [Reference] | 0.0197(−0.0208, 0.0602) | 0.3407 | |||
| Model 3c | −0.0009(−0.0612, 0.0593) | 0.9755 | −0.0035(−0.0483, 0.0413) | 0.8792 | [Reference] | 0.0210(−0.0194, 0.0613) | 0.3090 | |||
| Model 4d | −0.0105(−0.0694, 0.0484) | 0.7279 | −0.0032(−0.04692, 0.0406) | 0.8872 | [Reference] | 0.0173(−0.0222, 0.0568) | 0.3839 | |||
| Model 5e | −0.0107(−0.0696, 0.0482) | 0.7695 | −0.0041(−0.0479, 0.0398) | 0.8559 | [Reference] | 0.0166(−0.0229, 0.0561) | 0.4098 | |||
| Northern Region | ||||||||||
| Participants, No. | 406 | 702 | 1692 | 687 | ||||||
| Unadjusted | 0.0827(0.0189, 0.1465) | 0.0111 | 0.0484(−0.0034, 0.1003) | 0.0671 | [Reference] | 0.0733(0.0211, 0.1256) | 0.0029 | |||
| Model 1a | 0.0301(−0.0317, 0.0918) | 0.3402 | 0.0181(−0.0314, 0.0675) | 04738 | [Reference] | 0.0749(0.0253, 0.1245) | 0.0031 | |||
| Model 2 b | 0.0293(−0.0328, 0.0914) | 0.3550 | 0.0164(−0.0333, 0.0661) | 0.5173 | [Reference] | 0.0745(0.0246, 0.1244) | 0.0034 | |||
| Model 3c | 0.0210(−0.0412, 0.0831) | 0.5091 | 0.0156(−0.0340, 0.0629) | 0.5705 | [Reference] | 0.0715(0.0216, 0.1215) | 0.0050 | |||
| Model 4d | 0.0036(−0.0572, 0.0644) | 0.9086 | 0.0200(−0.0284, 0.0684) | 0.4187 | [Reference] | 0.0717(0.0229, 0.1205) | 0.0040 | |||
| Model 5e | 0.0034(−0.0574, 0.0642) | 0.9120 | 0.0210(−0.0274, 0.0695) | 0.3953 | [Reference] | 0.0699(0.0210, 0.1187) | 0.0051 | |||
Notes: Hs-CRP was normalized by natural-log transformation; the level of hs-CRP at eight hours of sleep was used as a reference. β (95% CI): Regression coefficients and 95% confidence interval of log hs-CRP across sleep duration categories. aModel 1 adjusted for age, sex, body mass index (BMI). bModel 2 adjusted for Model 1, educational attainment, residence and household income per capita. cModel 3 adjusted for Model 2, smoking status, alcohol drinking habits, physical activities levels and total energy intake. dModel 4 adjusted for Model 3, systolic and diastolic blood pressure, low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), triglycerides (TG), uric acid (UA), fasting serum glucose, fasting serum insulin. eModel 5: adjusted for Model 4 and health status related variables (the histories of diagnosed diabetes, hypertension, myocardial infarction, stroke and cancer, the uses of oral antidiabetic medicines, insulin, and antihypertensive drugs).
Abbreviations: CI, confidence interval; hs-CRP, high-sensitivity C-reactive protein.