Table 9.

Post Hoc Tests for the Association of PSRC1, CELSR2, and SORT1 SNPs with Variability on Warfarin Required Doses

Gene	SNP ID	Genotype		Initiation Dose P-value*	Maintenance Dose P-value*
PSRC1	rs646776	CC	CT	<0.0001	0.18
			TT	<0.0001	0.49
		CT	CC	<0.0001	0.18
			TT	0.479	0.26
		TT	CC	<0.0001	0.49 0.26
			CT	0.479
CELSR2	rs660240	CC	TC	0.326	0.07
			TT	0.0001	0.57
		TC	CC	0.326	0.07
			TT	<0.0001	0.14
		TT	CC	0.0001	0.57 0.14
			TC	<0.0001
	rs12740374	GG	GT	0.186	0.09 0.38
			TT	<0.0001
		GT	GG	0.186	0.09 0.09
			TT	<0.0001
		TT	GG	<0.0001	0.38
			GT	<0.0001	0.09
SORT1	rs602633	GG	GT	0.902	0.38 0.93
			TT	0.003
		GT	GG	0.902	0.38
			TT	0.002	0.56
		TT	GG	0.003	0.93
			GT	0.002	0.56

Note: *Post-Hoc multiple comparisons test with p< 0.05 is considered significant.