Table 14.

Post Hoc Tests for the Association of PSRC1, CELSR2, and SORT1 SNPs with INR Treatment Outcome

Gene	SNP ID	Genotype		Initiation INR P-value*	Maintenance INR P-value*
PSRC1	rs646776	CC	CT	<0.0001	0.18
			TT	<0.0001	0.09
		CT	CC	<0.0001	0.18 0.78
			TT	0.479
		TT	CC	<0.0001	0.09 0.78
			CT	0.479
CELSR2	rs660240	CC	TC	0.326	0.77
			TT	0.0001	0.09
		TC	CC	0.326	0.77
			TT	<0.0001	0.19
		TT	CC	0.0001	0.09
			TC	<0.0001	0.19
	rs12740374	GG	GT	0.186	0.65
			TT	<0.0001	0.17
		GT	GG	0.186	0.65
			TT	<0.0001	0.33
		TT	GG	<0.0001	0.17 0.33
			GT	<0.0001
SORT1	rs602633	GG	GT	0.902	0.58
			TT	0.003	0.02
		GT	GG	0.902	0.58
			TT	0.002	0.07
		TT	GG	0.003	0.02
			GT	0.002	0.07

Notes: *Post-Hoc multiple comparisons test with p<0.05 is considered significant. Compare initiation and maintenance dose among all genotypes.