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. 2020 Nov 17;13:11807–11818. doi: 10.2147/OTT.S274451

Figure 2.

Figure 2

MiR-1224-5p inhibits proliferation and invasion while promotes the apoptosis and autophagy of OS cells. (A) MTT assay to detect the cell proliferation in MG-63 cells and U2OS cells after transfection with NC mimic and miR-1224-5p mimic. (B) Cell colony formation assay to detect the cell viability in MG-63 cells and U2OS cells after transfection with NC mimic and miR-1224-5p mimic. (C) Flow cytometry to detect the apoptosis rate of MG-63 cells and U2OS cells after transfected with NC mimic and miR-1224-5p mimic. (D) Transwell to detect the invasive ability of MG-63 cells and U2OS cells after transfection with NC mimic and miR-1224-5p mimic. (E) Western blot to detect the expression level of autophagy-related proteins Beclin-1, LC3-II/I and p62 in MG-63 cells and U2OS cells after transfection with NC mimic and miR-1224-5p mimic. *P<0.05 vs mi-NC group.