Table 1.

Recent progresses in marine-derived antiviral natural products

Type	No	Source	Active compound
			No	Level
Alkaloids	1–3	Trichobotrys effuse	1–3	POTENT (HSV-1)
	4, 5	Neosartorya udagawae	4, 5	Moderate (H1N1)
	6	Penicillium sp.	6	Potent (HIV, HCV)
	7, 8	Penicillium raistrickii	7, 8	Potent (HCV)
	9	Streptomyces fradiae strain VITMK2	9	Potent (WSSV)
Quinones	10, 11	Aspergillus versicolor	10, 11	Significant (HSV-1)
	12	Aspergillus sydowii and Penicillium citrinum	12	Weak (H5N1)
	13, 14	Penicillium sp.	13	Potent (HBV)
			14	Significant (HBV)
	15	Nocardia alba KC710971	15	Moderate (NDV)
				Moderate (IBDV)
Peptides	16–27	Eutypella sp.	16–27	Significant (HIV-1)
	28–42	Eurotium rubrum	28–42	Weak (H1N1)
	43, 44	Pestalotiopsis sp.	43, 44	Potent (EV71)
	45, 46	Aspergillus sp.	45, 46	Potent (HSV-1)
Polyketones	47	Aspergillus sp.	47	Potent (H3N2, H1N1)
	48	Aspergillus sp.	48	Potent (H3N2)
	49	Pestalotiopsis sp.	49	Potent (EV71)
	50	Truncatella angustata	50	Potent (H1N1)
	51	Penicillium sp.	51	Weak (EV71)
	52–59	Spiromastix sp.	52–54	Strong (H1N1)
			55, 56, 58, 59	Moderate (H1N1)
			57	Weak (H1N1)
	60, 61	Streptomyces sp.	60, 61	Moderate (H1N1)
	62	Streptomyces koyangensis	62	Low (HSV)
Pyrones	63–68	Aspergillus iizukae	63	Potent (HSV-1)
				Weak (H1N1, HSV-2)
			64	Potent (H1N1, HSV-1, HSV-2)
			65, 67, 68	Weak HSV-1
			66	Weak (HSV-1, HSV-2)
	69–72	Streptomyces youssoufiensis	69–72	Moderate (H1N1, H3N2)
Sterols	73, 74	Cladosporium sp.	73	Potent (RSV)
			74	Weak (H3N2)
	75	Penicillium sp.	75	Potent (HIV, IAV)
Terpenoids	76	Talaromyces sp.	76	Potent (PRV)
	77–78	Penicillium sp.	77–78	Weak (H1N1)
	79	Stachybotrys chartarum	79	Significant (DENV)
	80	Stachybotry sp.	80	Moderate (EV71)
Others	81–84	Truncatella angustata	81, 82	Moderate (H1N1)
			83	Potent (H1N1)
				Weak (HIV)
			84	Weak (HIV)
	85	Eutypella sp.	85	Moderate (RSV)
	86	Pestalotiopsis vaccinii	86	Moderate (EV71)
	87	Aspergillus sydowii and Penicillium citrinum	87	Weak (H5N1)
	88	Streptomyces sp.	88	Low (H1N1)
	89	Streptomyces koyangensis	89	Mild (HSV)