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The peak signal-to-noise ratio (PSNR), structural similarity (SSIM), and root mean square error (RMSE) of the synthesized and low-count images compared to the ground-truth image. Site 1 data (used to train the original network in Chen et al. [17]) are also shown for comparison. Network training methods: A-direct application of pre-trained network; B-transfer learning starting with pre-trained network; C-training new network from scratch; D-training new network with combined datasets
