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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Eur J Nucl Med Mol Imaging. 2020 Jun 13;47(13):2998–3007. doi: 10.1007/s00259-020-04897-6

Table 3.

Accuracy, sensitivity, and specificity of the amyloid status readings (since a significant fraction of the low-dose images were uninterpretable [71/160 reads], they are not included in the analysis).

Value Method A Method B Method C Method D
(95% Cl)

Accuracy 78.8% 96.3% 98.1% 96.3%
(71.6%, 84.8%) (92.0%, 98.6%) (94.6%, 99.6%) (92.0%, 98.6%)

Sensitivity 60.5% 100% 98.7% 98.7%
(48.7%, 71.6%) (95.3%, 100%) (92.9%, 100%) (92.9%, 100%)

Specificity 95.2% 92.9% 97.6% 94.1%
(88.3%, 98.7%) (85.1%, 97.3%) (91.7%, 99.7%) (86.7%, 98.0%)

CI: confidence interval

Network training methods: A-direct application of pre-trained network; B-transfer learning starting with pre-trained network; C-training new network from scratch; D-training new network with combined datasets