Table 1.
Characteristics of Participants in the Analytic Sample
| Overall n = 1889 | Absence of Polypharmacy (<5 medications) n= 1356 | Presence of Polypharmacy (>5 medications) n=533 | |
|---|---|---|---|
| Age Mean (SD) | 65.1 (9.10) | 64.0 (9.0) | 68.0 (8.8) |
| Gender: Female, n (%) | 1048 (55.5%) | 715 (53.5) | 323 (60.6%) |
| Race: White, n (%) | 1584 (83.9%) | 1146 (84.5%) | 438 (82.2%) |
| BMI: Mean (SD) kg/m2 | 28.4 (4.8) | 28.1 (4.6) | 29.3 (5.3) |
| Depression* | |||
| High Depressive Symptoms, n (%) | 220 (11.6%) | 123 (9.1%) | 97 (18.2%) |
| WOMAC Pain Scale** | 2.7 (3.4) | 2.5 (3.2) | 3.4 (3.8) |
| Charlson Comorbidity Score*** | |||
| Presence of comorbidity, n (%) | 558 (29.5%) | 276 (20.4%) | 282 (52.9%) |
| K/L Grade, n (%)**** | |||
| 0 | 439 (23.2%) | 325 (24.0%) | 114 (21.4%) |
| 1 | 301 (15.9%) | 224 (16.5%) | 77 (14.5%) |
| 2 | 588 (31.1%) | 432 (31.9%) | 156 (29.3%) |
| 3 | 391 (20.7%) | 264 (19.5%) | 127 (23.8%) |
| 4 | 170 (9.0%) | 111 (8.2%) | 59 (11.1%) |
| Number of Prescription Medications | |||
| Median (IQR) | 3.0 (1.0, 5.0) | 2.0 (1.0, 3.0) | 6.0 (5.0, 8.0) |
| Weekly MVPA (Min) | |||
| Median (IQR) | 78.0 (26.8, 188.0) | 99.5 (37.3, 210.0) | 44.0 (10.0, 116.7) |
| Weekly Total PA (Min) | |||
| Median (IQR) | 2054.0 (1689.0, 2455.0) | 2106.5 (1756.0, 2484.) | 1916.0 (1520.2, 2389.0) |
SD – standard deviation; IQR – Interquartile Range
*
High Depressive symptoms as defined by modified Center for Epidemiological Studies Depression Scale ≥16
**
WOMAC: Western Ontario and McMaster University Osteoarthritis Index pain score modified to ask about right and left knee symptoms separately, range 0–20, worse knee reported
***
Charlson Comorbidity Index
****
K/L Grade: Kellgren and Lawrence Grade, scale ranges from 0–4 with 0 no radiographic knee OA and 4 most severe radiographic knee OA