Table 3.
Median Differences in Weekly Moderate-to-Vigorous Physical Activity Minutes between Persons with and without Polypharmacy
| Model 1 | Model 2 | Model 3 | |
|---|---|---|---|
| Characteristic | Median difference (95% CI) | Median difference (95% CI) | Median difference (95% CI) |
| Polypharmacy (>5 vs <5 medications) | −45.5 (−57.0, −37.5) | −17.2 (−26.1, −10.0) | −12.6, (−21.1, −4.7) |
| Average DailyWear Time, hours | 18.2 (14.6, 22.1) | 10.5 (7.1, 13.1) | 8.2 (5.2, 11.5) |
| Age, yrs | −4.5 (−4.9, −4.0) | −4.5 (−4.9, −4.0) | |
| Male | 42.0 (33.5, 53.0) | 45.5 (34.7, 55.2) | |
| Non-White | −15.4 (−23.8, −5.2) | −9.1 (−20.7, 2.9) | |
| BMI, kg/m2 | |||
| Under/Normal Weight | Reference | Reference | |
| Overweight | −20.3 (−32.4, −10.2) | −18.7 (−29.4, −7.7) | |
| Obese | −46.6 (−55.7, −37.3) | −43.2 (−55.3, −32.2) | |
| High Depressive Symptoms | −6.8 (−18.1, 7.4) | ||
| WOMAC Pain Scale | −1.6 (−2.9, −0.7) | ||
| KL Grade | |||
| 0 | Reference | ||
| 1 | −0.1 (−11.0, 14.6) | ||
| 2 | 4.3 (−7.3, 20.0) | ||
| 3 | −0.3 (−9.9, 12.4) | ||
| 4 | −6.5 (−23.5, 7.1) | ||
| Presence of Comorbidities | −9.8 (−18.5, −0.1) |
*
Values for number of prescriptions represent median change of weekly moderate-to-vigorous physical activity minutes with one unit increase. Depressed was classified as a CES-D score > 16. BMI = body mass index; Overweight had a BMI between 25 and 30 kg/m2; Obese had BMI values greater than 30 kg/m2; WOMAC = Western Ontario and McMaster Universities Osteoarthritis Index; KL= Kellgren/Lawrence