A, Representative images of immunohistochemistry for TOMM20, TIGAR, and MCT1 with CS1 and CS3 samples are shown. B, Percent positive cells and overall staining intensity were measured. Note that the percentage of tumor cells positive for TOMM20 and TIGAR is higher in high-grade chondrosarcoma (p<0.05) but not for MCT1 (p<0.23). C, Staining intensity for TOMM20, TIGAR, and MCT1 positively correlates with the percentage of tumor cells that are positive for TOMM20, TIGAR, and MCT1 respectively and higher grade tumors have higher staining intensity (p<0.05). *p<0.05