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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2020 Sep 10;1866(12):165962. doi: 10.1016/j.bbadis.2020.165962

Figure 6. Expression of mitochondrial markers in murine tumors.

Figure 6.

A, Quantification of TOMM20 protein levels normalized to β-actin control of tumors generated from EV control and TOMM20 overexpression. B, Quantification of MCT1 protein levels normalized to β-actin of tumors generated from control and EV TOMM20 overexpression. C, Quantification of TIGAR protein levels normalized to β-actin of tumors generated from EV control and TOMM20 overexpression. D, Quantification of mitoNEET protein levels normalized to β-actin of tumors generated from EV control and TOMM20 overexpression. E, Quantification of BCL2 protein levels normalized to β-actin of tumors generated from EV control and TOMM20 overexpression. F, Study schematic displaying the results of this study which include TOMM20 overexpression induces a more aggressive phenotype by increasing the expression of proteins involved in invasion and metastasis, proliferation, and resistance to apoptosis, promoting mitochondrial metabolism, and therapy resistance. EV control N=6, TOMM20 N=7, *p<0.05